Anti-Human OSMR/IL-31RB Reference Antibody (Vixarelimab, RUO) (HV716016)

Name: Anti-Human OSMR/IL-31RB Reference Antibody (Vixarelimab, RUO)
Brand: abinScience
SKU: HV716016
Price: 176 USD
Availability: InStock

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Overview

Catalog No.	HV716016
Description	Vixarelimab (HV716016) is a research-grade recombinant antibody targeting OSMRB. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG4-IgG1, Lambda
Expression system	Mammalian cells
Clonality	Monoclonal
Target	OSMRB, IL-31R subunit beta, Oncostatin-M-specific receptor subunit beta, Interleukin-31 receptor subunit beta, IL-31RB, IL-31R-beta, OSMR, IL-31 receptor subunit beta
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q99650
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	KPL-716, 30C6(N73D), BIIB069, BIIB-069, 2243320-83-2
Background	Oncostatin-M-specific receptor subunit beta (OSMR/IL-31RB) is a ~110 kDa protein. Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events.
Note	For research use only. Not suitable for clinical or therapeutic use.

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Bioactivity

SEC-HPLC detection for Research Grade Vixarelimab.

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Datasheet

Anti-Human OSMR/IL-31RB Reference Antibody (Vixarelimab, RUO).pdf

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Anti-Human OSMR/IL-31RB Reference Antibody (Vixarelimab, RUO) (HV716016)

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