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In Vivo Antibodies

abinScience in vivo antibodies are functional-grade reagents optimized for animal studies—azide-free, low endotoxin, sterile-filtered and aggregation-tested. Available in blocking, depleting, and neutralizing formats with lot-specific CoA reporting purity, endotoxin (LAL), and sterility. Includes IgG, F(ab')2, and Fc-engineered options. RUO

Why Researchers Choose abinScience

Animal-Compatible Azide-free, carrier-free, sterile buffer
Low Endotoxin LAL-tested, ≤0.1 EU/μg typical
Aggregation Control SEC-HPLC/DLS verified
Flexible Formats IgG, F(ab')2, Fc variants
Lot-Specific QC CoA with endotoxin, purity, sterility

Shop by Function

Shop by Application

Selection & Handling Guide

  1. Function: Select blocking, depleting, or neutralizing based on target and desired MoA.
  2. Format: Choose IgG for Fc-mediated effects (ADCC/CDC); F(ab')2 to eliminate FcγR binding.
  3. Dosing: Follow mg/kg guidelines from literature; common routes: i.p., i.v., s.c.
  4. QC Review: Check lot CoA for endotoxin, purity, and sterility before use.
  5. Controls: Always include matched isotype and vehicle controls.

Applications

Immunotherapy mechanism studies
Cell depletion in vivo
Cytokine blockade in disease models
Vaccine efficacy and immune modulation

Documents & QC

Lot-specific CoA: concentration, endotoxin, purity, sterility
Aggregation data (SEC-HPLC/DLS)
Recommended dosing and handling protocols

FAQs

How is an in vivo antibody different from standard lab grade?

In vivo products are azide-free, low endotoxin, sterile-filtered and aggregation-controlled, with carrier-free buffers and lot-level QC tailored to animal studies.

Should I choose IgG or F(ab')2?

Use IgG for Fc effector functions (depletion/engagement); use F(ab')2 when avoiding FcγR interactions is important.

Recommended endotoxin level?

Select low-endotoxin lots per protocol and record values from the lot-specific CoA; control endotoxin alongside dose and route.

Can these be used in humans?

No. All products are for Research Use Only (RUO) and not intended for diagnostic or therapeutic use.

What is InVivo Plus?

InVivo Plus is abinScience’s premium functional-grade specification with defined buffer, endotoxin and aggregation criteria; see the dedicated page for details.

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    Antibodies (510)
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    Mature virion in Complex [(VP0/1/3)5]12 (2)
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    entB/SEB (1)
    CD335/NCR1/NKp46 (1)
    IL22 (1)
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    EGFL7 (1)
    Capsid protein VP1 (2)
    HBsAg (5)
    Fusion glycoprotein/F Trimer (1)
    CD3E (2)
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    PF45/48 (2)
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    Outer capsid glycoprotein VP7 (1)
    CD115/CSF1R (1)
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    VSIG4/CRIg (1)
    IL31RA (1)
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    gE/Envelope glycoprotein E (1)
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    CD274/PD-L1 (5)
    ProteinUL128 & UL131A (1)
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    IL21 (1)
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    Spike glycoprotein (1)
    Protein prM/prM (3)
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    P domain (1)
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    TERM2 (1)
    CD274/PD-L1 & CD47/MER6 (1)
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    Procapsid [(VP0/1/3) 5] 12 (2)
    Capsid protein VP25 (1)
    SSEA4 (4)
    gH/gL Complexes (2)
    CD79B & CD3E (1)
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    IL31 (4)
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    env/Envpolyprotein (1)
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    RBD (13)
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    CXCL12/SDF-1 (1)
    IL20 (1)
    HSP90 (1)
    GPA33 (1)
    HLA-A*11:01 (1)
    Intermediate capsid protein VP6 (1)
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    CNR1/CB1 (3)
    HBEGF (1)
    iga/IgA1 protease (1)
    GDF2/BMP9 (1)
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    mature virion in complex (5)
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    E1 & E2 (gp35 & gp70) (3)
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    Flt3 ligand/FLT3LG (1)
    GP1 glycoprotein (2)
    F/Fusion glycoprotein F0 (8)
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    gD/Envelope glycoprotein D (2)
    F12/Coagulationfactor XII (1)
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    Fusion glycoprotein F0 (4)
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    Glycoprotein G (6)
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    VWF (1)
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    gB/Envelope glycoprotein B (8)
    ERBB3/HER3 (1)
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    L1/Major capsid protein L1 (2)
    Capsid protein (2)
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    CD99 (1)
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    Major surface glycoprotein G (3)
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    shiga toxin type 2A/stx2A (1)
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    lukF (1)
    CD152/CTLA4 & CD134/OX40 (1)
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    General (3)
    Plasmodium vivax (2)
    Enterovirus D68 (EV-D68) (2)
    Junin mammarenavirus (JUNV) (1)
    Dengue virus type 2 (DENV-2) (9)
    Clostridium botulinum (2)
    Reston ebolavirus (REBOV) (1)
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    Bundibugyo ebolavirus (BDBV) (1)
    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (21)
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    Mouse (65)
    Suid alphaherpesvirus 1 (SuHV-1/PRV) (3)
    Dengue virus type 1 (DENV-1) (1)
    Human adenovirus 3 (HAdV-3) (1)
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    Tai Forest ebolavirus (TAFV) (1)
    Hepatitis E virus/HEV (1)
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    Human cytomegalovirus (HCMV/HHV-5) (7)
    Enterovirus 71 (EV71) (4)
    Hantaan virus (HTNV) (2)
    Varicella-zoster virus (VZV/HHV-3) (4)
    Dog (11)
    Dengue virus type 3 (DENV-3) (1)
    Middle East respiratory syndrome-related coronavirus (MERS-CoV) (5)
    Zika virus (ZIKV) (2)
    Candida albicans (1)
    Cat (1)
    Human astrovirus-8 (HAtVs) (1)
    Streptococcus pneumoniae (1)
    Coxsackievirus A16 (CVA16) (2)
    Human parvovirus B19 (HPV B19) (3)
    Orthohantavirus puumalaense (PUUV) (1)
    Sudan ebolavirus (SEBOV) (1)
    Machupo virus (MACV) (1)
    Human respiratory syncytial virus (HRSV) (14)
    Human hepatitis A virus (HHAV) (1)
    Puumala virus (PUUV) (2)
    Nipah virus (NiV) (13)
    Dengue virus type 4 (DENV-4) (1)
    Lassa virus (LASV) (1)
    Dobrava-Belgrade virus (DOBV) (2)
    Human betacoronavirus 2c EMC/2012 (HCoV-EMC) (2)
    Human papillomavirus 6 (HPV6) (1)
    Porcine circovirus 2 (PCV2) (2)
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    Brazilian scorpion (1)
    Hepatitis C Virus (HCV) (9)
    Human papillomavirus 16 (HPV16) (2)
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    Hepatitis B virus genotype A (HBV-A) (6)
    Zaire ebolavirus (ZEBOV) (6)
    Andes virus (ANDV) (2)
    Human papillomavirus 58 (HPV58) (3)
    Severe acute respiratory syndrome coronavirus (SARS-CoV) (3)
    Campylobacter jejuni subsp. (1)
  • Applications
    0 selected
    in vivo (1)
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    Research in vivo (2)
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    in vitro PD-L1 blockade (3)
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    in vivo research (1)
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    WB (22)
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    IP (5)
    IHC (6)
    RIA (1)
    FACS (2)
    Nneutralization (1)
    ELISA (424)
    Cell Deplete (1)
    ICC (1)
    in vivo blocking of PD-1/PD-L signaling (2)
    Functional assay (2)
    in vivo study (4)
    Neutralization (388)
  • Reactivity
    0 selected
    Mouse (12)
    Puumala virus (1)
    Human (16)
    Influenza B virus (1)
    Coxsackievirus B1 (CVB1) (3)
    Chikungunya virus (1)
  • Host species
    0 selected
    Hamster (1)
    Alpaca (5)
    Mouse (161)
    Dog (8)
    Cat (1)
    Human (319)
    Rat (11)
  • Clonality
    0 selected
    Monoclonal (510)
  • Conjugate
    0 selected
    Unconjugated (510)

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