XtenNano® Nanobodies | VHH Single-Domain Antibodies

Discover 900+ XtenNano® recombinant nanobodies — single-domain antibodies (VHH) derived from camelid heavy-chain-only immunoglobulins. At just ~15 kDa, nanobodies offer superior tissue penetration, exceptional thermal/chemical stability, and access to hidden epitopes unreachable by conventional IgG antibodies. Ideal for super-resolution microscopy, intracellular targeting, and affinity purification. All products are designated Research Use Only (RUO) — not intended for diagnostic or therapeutic procedures. RUO

Why Researchers Choose abinScience

Ultra-Small (~15 kDa) One-tenth the size of conventional IgG — enabling deeper tissue penetration, faster clearance, and access to sterically restricted epitopes in crowded molecular environments.

Super-Resolution Imaging Smaller labeling radius improves localization precision in STORM, PALM, and STED microscopy. Pre-conjugated to fluorophores for direct use in advanced imaging workflows.

High Stability Resistant to extreme pH, temperature, and chemical denaturants. Suitable for harsh fixation protocols, intracellular staining, and applications where conventional antibodies lose activity.

Recombinant & Sequence-Defined Every XtenNano® nanobody is recombinantly produced with a defined sequence — ensuring absolute lot-to-lot reproducibility and enabling genetic fusion to reporters or tags.