Cervical Cancer Reagents | abinScience

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Virtually all cervical cancers are HPV-driven. Beyond HPV detection and p16 surrogate testing, PD-1 checkpoint inhibitors and emerging ADCs are expanding treatment options for advanced disease. abinScience provides validated antibodies, recombinant proteins, and biosimilar-grade reference proteins for the targets listed below. RUO

Key Biomarkers & Targets

HPV

Human Papillomavirus

HPV E6/E7 drive cervical carcinogenesis; L1 is the vaccine target. 130 products. Validated: Blocking, ELISA, IHC, WB.

Antibodies • Biosimilars • Proteins

p16 / CDKN2A

Tumor Suppressor

p16 overexpression is the IHC surrogate for HPV integration. 55 products. Validated: Blocking, ELISA, FC, IF, IHC, WB.

Antibodies • Biosimilars • Proteins

PD-L1

CD274

Pembrolizumab approved for PD-L1+ cervical cancer. 130 products. Validated: Blocking, ELISA, FC, IF, IHC, WB.

Antibodies • Biosimilars • Proteins

TROP2

TACSTD2

ADC target being evaluated in cervical cancer. 32 products. Validated: ELISA, FC, IHC, WB.

Antibodies • Biosimilars • Proteins

Nectin-4

PVRL4

ADC target being evaluated in cervical cancer. 29 products. Validated: ELISA, FC, IHC, WB.

Antibodies • Biosimilars • Proteins

VEGF

Angiogenesis

Bevacizumab backbone of cervical cancer combination therapy. 122 products. Validated: Blocking, ELISA, FC, IHC, SPR, WB.

Antibodies • Biosimilars • Proteins

B7-H3 / CD276

Immune Checkpoint

Overexpressed in cervical SCC; emerging target. 39 products. Validated: ELISA, FC, IHC, WB.

Antibodies • Biosimilars • Proteins

EGFR

ErbB1

EGFR pathway in cervical cancer. 108 products. Validated: Blocking, ELISA, FC, IHC, SPR, WB.

Antibodies • Biosimilars • Proteins

Why Researchers Choose abinScience

IHC-Validated AntibodiesAntibodies with IHC validation available for: HPV, p16, PD-L1, TROP2, Nectin-4, VEGF. See individual product pages for clone details and recommended dilutions.

Flow Cytometry ReadyFC-validated antibodies available for: p16, PD-L1, TROP2, Nectin-4, VEGF, B7-H3. Multiple conjugates (FITC, APC, PE, PerCP) offered for select clones.

Research-Grade BiosimilarsBiosimilar-grade reference proteins with ELISA and FACS validation for: HPV, p16, PD-L1, TROP2, Nectin-4.

Original Manufacturer PricingDirect-from-manufacturer pricing with no distributor markup. Bulk and custom conjugation options available.

Common Research Applications

IHC-based biomarker detection: We offer IHC-validated antibodies for HPV, p16, PD-L1, TROP2, Nectin-4. See product pages for validated species and recommended dilutions.
Flow cytometry immunophenotyping: FC-validated antibodies available for p16, PD-L1, TROP2, Nectin-4, VEGF. Select clones offered in FITC, APC, PE, and PerCP conjugates.
Functional and blocking assays: Antibodies with blocking/neutralization validation available for: HPV, p16, PD-L1, VEGF.
Biosimilar comparability: Research-grade biosimilar proteins (ELISA/FACS/Functional assay validated) available for HPV, p16, PD-L1, TROP2.

Documents & QC Data

Download product datasheets, validation images (WB/IHC/IF/FC), CoA, and application protocols on each product page. All data is lot-specific.

FAQs

What HPV reagents do you offer?

We offer 100 detection antibodies, 1 research-grade biosimilar proteins, and 29 recombinant proteins. Validated applications include: Blocking, ELISA, IHC, WB. Available clones include: Polyclonal (ELISA, IHC, WB; unconjugated), SAA2229 (ELISA, IHC, WB; unconjugated), SAA2454 (ELISA, IHC, WB; unconjugated). Research-grade biosimilar proteins also available (e.g., Anti-HPV18 L1/Major capsid protein L1 An).

What PD-L1 reagents do you offer?

We offer 58 detection antibodies, 59 research-grade biosimilar proteins, and 13 recombinant proteins. Validated applications include: Blocking, ELISA, FC, IF, IHC, WB. Available clones include: 22C3 (ELISA, FC, IHC, WB; APC, FITC, PE), Polyclonal (ELISA, IHC, WB; unconjugated), SP142 (ELISA, IHC, WB; unconjugated). Research-grade biosimilar proteins also available (e.g., Envafolimab, Pacmilimab, Cosibelimab).

What VEGF reagents do you offer?

We offer 66 detection antibodies, 39 research-grade biosimilar proteins, and 17 recombinant proteins. Validated applications include: Blocking, ELISA, FC, IHC, SPR, WB. Available clones include: Polyclonal (ELISA, IHC, WB; unconjugated), 1A169 (ELISA, IHC, WB; unconjugated), YW64.3 (ELISA, FC; APC, FITC, PE). Research-grade biosimilar proteins also available (e.g., Vesencumab, Navicixizumab, Dilpacimab).

What EGFR reagents do you offer?

We offer 45 detection antibodies, 49 research-grade biosimilar proteins, and 14 recombinant proteins. Validated applications include: Blocking, ELISA, FC, IHC, SPR, WB. Available clones include: SAA2220 (ELISA, FC, IHC, WB; APC, FITC, PE), Polyclonal (ELISA, IHC, WB; unconjugated), 11F8 (ELISA, FC, WB; APC, FITC, PE). Research-grade biosimilar proteins also available (e.g., Modotuximab, Tomuzotuximab, Depatuxizumab).

Can I get custom antibodies for novel targets?

Yes — our parent company AtaGenix provides full custom antibody development from immunogen design through hybridoma production and characterization, including targets not yet in our catalog.

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