Anti-IGF1 Polyclonal Antibody (HY095014)

Name: Anti-IGF1 Polyclonal Antibody
Brand: abinScience
SKU: HY095014
Price: 168 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.

HY095014

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human IGF1 (Gly49-Ala118).

Target

IGF-I, IGF1, Mechano growth factor, MGF, Insulin-like growth factor I, IBP1, Somatomedin-C

Purification

Purified by antigen affinity column.

Accession

P05019

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Insulin-like growth factor 1 (IGF1) is a ~21 kDa protein. The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exocytosis of IGF1 is required for sensory perception of smell in the olfactory bulb.

1. Zoidis, E. et al. (2011) Molecular and cellular biochemistry 348, 33-42. PMID: 21076856

2. Shcheglovitov, A. et al. (2013) Nature 503, 267-71. PMID: 24132240

3. Saegusa, J. et al. (2009) The Journal of biological chemistry 284, 24106-14. PMID: 19578119

4. Fujita, M. et al. (2012) The Journal of biological chemistry 287, 12491-500. PMID: 22351760

5. Fujita, M. et al. (2013) The Journal of biological chemistry 288, 3059-69. PMID: 23243309

6. Fujita, M. et al. (2013) The Journal of biological chemistry 288, 19593-603. PMID: 23696648

Note

For research use only.

Images

References

Datasheet

Anti-IGF1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-IGF1 Polyclonal Antibody (HY095014)

Overview

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References

Datasheet

SDS

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