Anti-HHV-5/HCMV gH/UL75 Recombinant Antibody (2-4#) (VK705013)

Name: Anti-HHV-5/HCMV gH/UL75 Recombinant Antibody (2-4#)
Brand: abinScience
SKU: VK705013
Price: 191 USD
Availability: InStock

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100ug
1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

VK705013

Species reactivity

Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5)

Applications

ELISA, FCM, IF, WB

Host species

Human

Isotype

IgG1

Clone ID

2-4#

Clonality

Monoclonal

Target

gH, Envelope glycoprotein H

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P12824

RRID

Anti-HHV-5/HCMV gH/UL75 Antibody (2-4#) (abinScience Cat# VK705013, RRID:AB_3727213)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Envelope glycoprotein H (gH/UL75) is a ~84 kDa protein. The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis. In human cytomegalovirus, forms two distinct complexes to mediate viral entry, a trimer and a pentamer at the surface of the virion envelope. The gH-gL-gO trimer is required for infection in fibroblasts by interacting with host PDGFRA, and in glioblastoma cells by interacting with host EPHA2.

Note

For research use only.

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