Anti-HHV-5/HCMV glycoprotein H/gH Polyclonal Antibody (VK665014)

Name: Anti-HHV-5/HCMV glycoprotein H/gH Polyclonal Antibody
Brand: abinScience
SKU: VK665014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

VK665014

Description

Anti-HHV-5/HCMV glycoprotein H/gH Polyclonal Antibody (VK665014) is a rabbit polyclonal antibody detecting HHV-5/HCMV glycoprotein H/gH. Suitable for Human cytomegalovirus.

Species reactivity

Human cytomegalovirus (HCMV) (HHV-5) (Human herpesvirus 5)

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant HHV-5/HCMV glycoprotein H/gH (Phe298-Val605).

Target

Envelope glycoprotein H, UL75, gH

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

P12824

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Background

Envelope glycoprotein H (gH) is a ~84 kDa protein. The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis. In human cytomegalovirus, forms two distinct complexes to mediate viral entry, a trimer and a pentamer at the surface of the virion envelope. The gH-gL-gO trimer is required for infection in fibroblasts by interacting with host PDGFRA, and in glioblastoma cells by interacting with host EPHA2.

Note

For research use only

Images

References

Datasheet