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Anti-Human F7 Polyclonal Antibody (HY060024)

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Overview
Catalog No.HY060024
Description
Anti-Human F7 Polyclonal Antibody (HY060024) is a rabbit polyclonal antibody detecting Human F7. Suitable for Human.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human F7 (Ile213-Pro466).
Target Coagulation factor VII, EC:3.4.21.21, Eptacog alfa, F7, Factor VII heavy chain, Factor VII light chain, Proconvertin, SPCA, Serum prothrombin conversion accelerator
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P08709
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Coagulation factor VII (F7) is a ~51 kDa protein. Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa also converts factor IX to factor IXa in the presence of tissue factor and calcium.

1. Osterud, B. et al. (1977) Proceedings of the National Academy of Sciences of the United States of America 74, 5260-4. PMID: 271951
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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