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Anti-Human β-tryptase/TPSAB1 Recombinant Antibody (E104.v1) (HS931013)

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Overview
Catalog No.HS931013
Species reactivityHuman
ApplicationsELISA
Host speciesHuman
IsotypeIgG1, kappa
Clone IDE104.v1
Clonality Monoclonal
Target EC:3.4.21.59, TPS1, TPS2, TPSAB1, TPSB1, Tryptase I, Tryptase alpha-1, Tryptase alpha/beta-1, Tryptase-1
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q15661
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitution Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Tryptase alpha/beta-1 (β-tryptase/TPSAB1) is a ~30 kDa protein. Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates.

1. Jackson, NE. et al. (2008) The Journal of biological chemistry 283, 34178-87. PMID: 18854315
Note For research use only
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