Anti-Human IL-18 R beta/IL-1 R7 Recombinant Antibody (Roche patent anti-IL-18Rα) (HF719013)

Name: Anti-Human IL-18 R beta/IL-1 R7 Recombinant Antibody (Roche patent anti-IL-18Rα)
Brand: abinScience
SKU: HF719013
Price: 191 USD
Availability: InStock

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100ug
1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HF719013

Description

Anti-Human IL-18 R beta/IL-1 R7 Recombinant Antibody (Roche patent anti-IL-18Rα) (HF719013) is a human monoclonal antibody detecting IL-18 R beta/IL-1 R7 in ELISA. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.

Species reactivity

Human

Applications

ELISA

Host species

Human

Clonality

Monoclonal

Isotype

IgG1, kappa

Clone ID

Roche patent anti-IL-18Rα

Target

CD218 antigen-like family member A, CD218a, CDw218a, EC:3.2.2.6, IL-18R-1, IL-18R-alpha, IL-18R1, IL-18Ralpha, IL-1Rrp, IL1 receptor-related protein, IL18R1, IL1R-rp, IL1RRP, Interleukin-18 receptor 1, Interleukin-18 receptor alpha

Endotoxin level

< 10 EU/mg as determined by LAL method.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q13478

Form

Liquid

Storage buffer

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Interleukin-18 receptor accessory protein (CD218b/IL18RAP) is a ~68 kDa protein. Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation. May play a role in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (Probable).

1. Kato, Z. et al. (2003) Nature structural biology 10, 966-71. PMID: 14528293

2. Tsutsumi, N. et al. (2014) Nature communications 5, 5340. PMID: 25500532

3. Born, TL. et al. (1998) The Journal of biological chemistry 273, 29445-50. PMID: 9792649

Note

For research use only.

Images

References

Datasheet

Anti-Human IL-18 R beta/IL-1 R7 Recombinant Antibody (Roche patent anti-IL-18Rα).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human IL-18 R beta/IL-1 R7 Recombinant Antibody (Roche patent anti-IL-18Rα) (HF719013)

Overview

Images

References

Datasheet

SDS