

| Catalog No. | HY476036 |
|---|---|
| Description |
Anti-Human aPC/Activated protein C Reference Antibody (Inuxucibart, RUO) (HY476036) is a human monoclonal antibody detecting PROC,aPC/Activated protein C.
|
| Species reactivity | Human |
| Applications | ELISA, FCM, Functional assay |
| Host species | Human |
| Clonality | Monoclonal |
| Isotype | IgG4, kappa |
| Target | Activation peptide, Anticoagulant protein C, Autoprothrombin IIA, Blood coagulation factor XIV, EC:3.4.21.69, PROC, Vitamin K-dependent protein C, Vitamin K-dependent protein C heavy chain, Vitamin K-dependent protein C light chain |
| Endotoxin level | < 10 EU/mg |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P04070 |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term from the date of receipt.. |
| Alternate Names | CAS: 3078212-80-0 |
| Background | Vitamin K-dependent protein C (APC/Activated protein C) is a ~52 kDa protein. Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. 1. Kovács, KB. et al. (2015) Thrombosis research 135, 718-26. PMID: 25618265 2. Cao, Q. et al. (2025) Nature 639, 816-824. PMID: 39880037 3. Ding, Q. et al. (2015) Blood 125, 2428-34. PMID: 25651845 |
| Note | For research use only. |




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