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Anti-Human CD158k/KIR3DL2 Antibody (SAA0064) (HW633107)

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Anti-Human CD158k/KIR3DL2 Antibody (SAA0064)

Anti-Human CD158k/KIR3DL2 Antibody (SAA0064)

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Overview

Catalog No.	HW633107
Description	Anti-Human CD158k/KIR3DL2 Antibody (SAA0064) [SAA0064] (HW633107) is a mouse monoclonal antibody detecting KIR3DL2 in FCM. Suitable for Human. Highlights ●Flow Cytometry — Validated for flow cytometry applications.
Species reactivity	Human
Applications	FCM
Host species	Mouse
Isotype	IgG1, kappa
Clone ID	SAA0064
Clonality	Monoclonal
Target	CD158K, MHC class I NK cell receptor, NKAT4, Natural killer-associated transcript 4, KIR3DL2, p70 NK receptor CL-5, CD158k, p70 natural killer cell receptor clone CL-5, CD158 antigen-like family member K, Killer cell immunoglobulin-like receptor 3DL2, NKAT-4
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P43630
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Killer cell immunoglobulin-like receptor 3DL2 (CD158k/KIR3DL2) is a ~50 kDa protein. Receptor on natural killer (NK) cells and T cells for MHC class I molecules. Upon binding of peptide-free HLA-F open conformer, negatively regulates NK and T cell effector functions. Acts as a receptor on astrocytes for HLA-F. Through interaction with HLA-F, may protect motor neurons from astrocyte-induced toxicity. 1. Goodridge, JP. et al. (2013) Journal of immunology (Baltimore, Md. : 1950) 191, 3553-62. PMID: 24018270 2. Dulberger, CL. et al. (2017) Immunity 46, 1018-1029.e7. PMID: 28636952 3. Song, S. et al. (2016) Nature medicine 22, 397-403. PMID: 26928464
Note	For research use only.

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SDS-PAGE

SDS-PAGE for Anti-Human CD158k/KIR3DL2 Antibody (SAA0064)

References

Datasheet

Anti-Human CD158k/KIR3DL2 Antibody (SAA0064).pdf

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Anti-Human CD158k/KIR3DL2 Antibody (SAA0064)