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Anti-Human CD195/CCR5 Antibody (PRO-140) (HW412107)

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Anti-Human CD195/CCR5 Antibody (PRO-140)

Anti-Human CD195/CCR5 Antibody (PRO-140)

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Datasheet

Overview

Catalog No.	HW412107
Description	Anti-Human CD195/CCR5 Antibody (PRO-140) [PRO-140] (HW412107) is a human monoclonal antibody detecting CD195 in FCM. Suitable for Human. Highlights ●Flow Cytometry — Validated for flow cytometry applications.
Species reactivity	Human
Applications	FCM
Host species	Human
Isotype	IgG4, kappa
Clone ID	PRO-140
Clonality	Monoclonal
Target	C-C CKR-5, CC-CKR-5, CMKBR5, HIV-1 fusion coreceptor, CHEMR13, CCR5, C-C chemokine receptor type 5, CD195, CCR-5
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P51681
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	C-C chemokine receptor type 5 (CD195/CCR5) is a ~40 kDa protein. Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Participates in T-lymphocyte migration to the infection site by acting as a chemotactic receptor. 1. Sharapova, TN. et al. (2018) Acta naturae 10, 115-120. PMID: 30713770
Note	For research use only.

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Bioactivity

SEC-HPLC detection for Anti-Human CD195/CCR5 Antibody (PRO-140).

References

Datasheet

Anti-Human CD195/CCR5 Antibody (PRO-140).pdf

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Anti-Human CD195/CCR5 Antibody (PRO-140)