Anti-Mouse NKG2D Antibody (MI-6) (MB123107)

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Catalog No.	MB123107
Description	Anti-Mouse NKG2D Antibody (MI-6) [MI-6] (MB123107) is a rat monoclonal antibody detecting Nkg2d in Blocking, ELISA, FCM. Suitable for Mouse. Highlights ●Multi-Application — Validated across multiple applications. ●Flow Cytometry — Validated for flow cytometry applications.
Species reactivity	Mouse
Applications	Blocking, ELISA, FCM
Host species	Rat
Isotype	IgG2a, lambda
Clone ID	MI-6
Clonality	Monoclonal
Target	NKG2-D type II integral membrane protein, Killer cell lectin-like receptor subfamily K member 1, NK cell receptor D, NKG2-D-activating NK receptor, CD314, Klrk1, Nkg2d
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	O54709
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.09% Sodium azide. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	NKG2-D type II integral membrane protein (CD314/KLRK1) is a ~26 kDa protein. Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, culminating in the expression of TNF.
Note	For research use only.

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Anti-Mouse NKG2D Antibody (MI-6).pdf

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Anti-Mouse NKG2D Antibody (MI-6) (MB123107)

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