Anti-Human CD261/TNFRSF10A/DR4 Recombinant Antibody (SAA0083), APC (HT017137)

Name: Anti-Human CD261/TNFRSF10A/DR4 Recombinant Antibody (SAA0083), APC
Brand: abinScience
SKU: HT017137
Price: 290 USD
Availability: InStock

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Overview

Catalog No.	HT017137
Species reactivity	Human
Applications	FCM
Host species	Human
Isotype	IgG1
Clone ID	SAA0083
Conjugation	APC
Clonality	Monoclonal
Target	TNF-related apoptosis-inducing ligand receptor 1, APO2, Death receptor 4, TRAIL receptor 1, TRAIL-R1, CD261, DR4, TRAILR1, TNFRSF10A, Tumor necrosis factor receptor superfamily member 10A
Endotoxin level	Please contact with the lab for this information.
Accession	O00220
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Tumor necrosis factor receptor superfamily member 10A (CD261/TNFRSF10A) is a ~50 kDa protein. Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. 1. Ramamurthy, V. et al. (2015) Acta crystallographica. Section F, Structural biology communications 71, 1273-81. PMID: 26457518 2. Chyuan, IT. et al. (2024) Journal of biomedical science 31, 33. PMID: 38532423 3. Rossin, A. et al. (2009) The Biochemical journal 419, 185-92, 2 p following 192. PMID: 19090789 4. Chaudhary, PM. et al. (1997) Immunity 7, 821-30. PMID: 9430227
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Human CD261/TNFRSF10A/DR4 Recombinant Antibody (SAA0083), APC.pdf

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Anti-Human CD261/TNFRSF10A/DR4 Recombinant Antibody (SAA0083), APC (HT017137)

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