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Anti-Human CD307e/FCRL5 Antibody (SAA0316), PE (HV698127)

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Overview

Catalog No.	HV698127
Description	Anti-Human CD307e/FCRL5 Antibody (SAA0316), PE [SAA0316] (HV698127) is a mouse monoclonal antibody detecting CD307e in ELISA, FCM. Suitable for Human. Highlights ●Flow Cytometry — Validated for flow cytometry applications.
Species reactivity	Human
Applications	ELISA, FCM
Host species	Mouse
Isotype	IgG2a, kappa
Clone ID	SAA0316
Conjugation	PE
Clonality	Monoclonal
Target	FcRL5, FCRH5, FCRL5, Fc receptor homolog 5, FcRH5, CD307e, FcR-like protein 5, IRTA2, Immune receptor translocation-associated protein 2, BXMAS1, Fc receptor-like protein 5, CD307
Endotoxin level	Please contact with the lab for this information.
Accession	Q96RD9
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Fc receptor-like protein 5 (CD307e/FCRL5) is a ~106 kDa protein. Plays an important role in B-cell response to antigen that acts both as a negative or positive coreceptor. Inhibits B-cell receptor (BCR) signaling in the absence of CR2 stimulation but engagement with CR2 and the BCR lead to a superior calcium response compared to CR2 and BCR costimulation. May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells. May play a role in fertilization. 1. Franco, A. et al. (2018) International immunology 30, 569-578. PMID: 30107486
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Datasheet

Anti-Human CD307e/FCRL5 Antibody (SAA0316), PE.pdf

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Anti-Human CD307e/FCRL5 Antibody (SAA0316), PE