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Research Grade Enavatuzumab (HV811016)

Research Grade Enavatuzumab
Research Grade Enavatuzumab
Research Grade Enavatuzumab
Research Grade Enavatuzumab
Research Grade Enavatuzumab
Research Grade Enavatuzumab
Price(USD): $
Spec:
  • 100ug
  • 1mg
Number:
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  • Overview

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  • References

  • Datasheet

Overview
Catalog No.HV811016
Description
Enavatuzumab (HV811016) is a research-grade recombinant antibody targeting CD266. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHumanized
IsotypeIgG1-kappa
Expression system Mammalian Cells
Clonality Monoclonal
Target FGF-inducible 14, TNFRSF12A, FN14, CD266, TweakR, Fibroblast growth factor-inducible immediate-early response protein 14, Tweak-receptor, Tumor necrosis factor receptor superfamily member 12A
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q9NP84
Form Liquid
Storage buffer 0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate NamesPDL192, 1062149-33-0
Background

Tumor necrosis factor receptor superfamily member 12A (CD266/TNFRSF12A) is a ~13 kDa protein. Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Research Grade Enavatuzumab

    Bioactivity

    SEC-HPLC detection for Research Grade Enavatuzumab.

  • Research Grade Enavatuzumab

    SDS-PAGE

    SDS-PAGE for Research Grade Enavatuzumab.

  • Research Grade Enavatuzumab

    Western blot

    Western blot analysis was performed using anti-CD266/TNFRSF12A monoclonal antibody at 1ug/mL on various samples.
    Lane 1: recombinant human CD266/TNFRSF12A (Catalog No: HV811011)
    Lane 2: negative control

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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