Research Grade Anti-Human APC/Activated protein C (TPP-4885/BAY1896502) (HY476026)

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100ug
1mg

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Overview

Catalog No.	HY476026
Description	Anti-Human APC/Activated protein C (TPP-4885/BAY1896502) (HY476026) is a research-grade recombinant antibody targeting Anticoagulant protein C. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Humanized
Isotype	IgG2
Clone ID	TPP-4885/BAY1896502
Expression system	Mammalian Cells
Clonality	Monoclonal
Target	Anticoagulant protein C, Vitamin K-dependent protein C, Blood coagulation factor XIV, Autoprothrombin IIA, PROC
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P04070
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names	TPP-2312, BAY1316786
Background	Vitamin K-dependent protein C (APC/Activated protein C) is a ~52 kDa protein. Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. 1. Kovács, KB. et al. (2015) Thrombosis research 135, 718-26. PMID: 25618265 2. Cao, Q. et al. (2025) Nature 639, 816-824. PMID: 39880037 3. Ding, Q. et al. (2015) Blood 125, 2428-34. PMID: 25651845
Note	For research use only. Not suitable for clinical or therapeutic use.