| Catalog No. | HC298046 |
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| Species reactivity | Human |
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| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
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| Host species | Human |
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| Isotype | IgG2-kappa |
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| Expression system | Mammalian Cells |
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| Clonality | Monoclonal |
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| Target | Selectin P ligand, PSGL-1, SELPLG, CD162, P-selectin glycoprotein ligand 1 |
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| Endotoxin level | Please contact the lab for this information. |
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| Purity | >95% purity as determined by SDS-PAGE. |
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| Purification | Protein A/G purified from cell culture supernatant. |
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| Accession | Q14242 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS, pH 7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
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| Alternate Names | 2769758-59-8 |
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| Background | Cepeprubart is an anti-SELPLG human IgG2 κ monoclonal antibody. Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002).
• Soluble P-selectin rescues mice from anthrax lethal toxin-induced mortality through PSGL-1 pathway-mediated correction of hemostasis., PMID:28102766
• PD-1 Immune Checkpoint Blockade and PSGL-1 Inhibition Synergize to Reinvigorate Exhausted T Cells., PMID:35774790
• Impact of variables of the P-selectin - P-selectin glycoprotein ligand-1 axis on leukocyte-platelet interactions in cardiovascular disease., PMID:25428141
• Lnc-SELPLG-2:1 enhanced osteosarcoma oncogenesis via hsa-miR-10a-5p and the BTRC cascade., PMID:36199080
• Soluble P-selectin rescues viper venom-induced mortality through anti-inflammatory properties and PSGL-1 pathway-mediated correction of hemostasis., PMID:27779216
• Contrasting roles of PSGL-1 and PD-1 in regulating T-cell exhaustion and function during chronic viral infection., PMID:39912665
• SELPLG gene polymorphisms in relation to plasma SELPLG levels and coronary artery disease., PMID:14641238
• High levels of platelet-monocyte aggregates after valve replacement for aortic stenosis: relation to soluble P-selectin and P-selectin glycoprotein ligand-1 genes., PMID:21816455
• Genomic organization and chromosomal localization of the gene encoding human P-selectin glycoprotein ligand., PMID:7541799
• SELPLG Expression Was Potentially Correlated With Metastasis and Prognosis of Osteosarcoma., PMID:35153625
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| Note | For research use only. Not suitable for clinical or therapeutic use. |
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