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Research Grade Tisotumab (HB058016)

Price(USD): $
Spec:
  • 100ug
  • 1mg
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  • Datasheet
Overview
Catalog No.HB058016
Species reactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHuman
IsotypeIgG1-kappa
Expression systemMammalian Cells
ClonalityMonoclonal
TargetTissue factor, CD142, F3, Thromboplastin, Coagulation factor III, TF
Endotoxin levelPlease contact the lab for this information.
Purity>95% purity as determined by SDS-PAGE.
PurificationProtein A/G purified from cell culture supernatant.
AccessionP13726
FormLiquid
Storage buffer0.01M PBS, pH 7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate NamesHuMax-TF-ADC, TF-011-MMAE, HuMax-TF, 1418628-81-5
BackgroundHY-P990942 is an F3-targeting IgG1κ type human antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001).
• Elevated coagulation factor levels affect the tissue factor-threshold in thrombin generation., PMID:30408635
• Improved MSC Minimal Criteria to Maximize Patient Safety: A Call to Embrace Tissue Factor and Hemocompatibility Assessment of MSC Products., PMID:35641163
NoteFor research use only. Not suitable for clinical or therapeutic use.
Images
  • SEC-HPLC

    SEC-HPLC detection for Research Grade Tisotumab.

  • Bioactivity

    Detects CD142/F3/TF in indirect ELISAs.

  • SDS-PAGE

    SDS-PAGE for Research Grade Tisotumab.

  • Flow CytoMetry

    Flow-cytometry using anti-human CD142 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human CD142 monoclonal antibody (Catalog: HB058016) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.

References

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