Anti-Human Coagulation factor III/Tissue factor Reference Antibody (MRG 004A, RUO) (HB058046)

Name: Anti-Human Coagulation factor III/Tissue factor Reference Antibody (MRG 004A, RUO)
Brand: abinScience
SKU: HB058046
Price: 326 USD
Availability: InStock

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Overview

Catalog No.	HB058046
Description	Anti-Human CD142/F3/TF (MRG 004A) (HB058046) is a research-grade recombinant antibody targeting CD142. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG
Clone ID	MRG 004A
Expression system	Mammalian cells
Clonality	Monoclonal
Target	Tissue factor, CD142, F3, Thromboplastin, Coagulation factor III, TF
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P13726
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	MRG-004A, MRG004A, MRG004A
Background	Tissue factor (CD142/F3) is a ~33 kDa protein. Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. CD142 is the therapeutic target of tisotumab vedotin (Tivdak).
Note	For research use only. Not suitable for clinical or therapeutic use.