Anti-Human Endoglin/CD105 Polyclonal Antibody (HB604014)

Name: Anti-Human Endoglin/CD105 Polyclonal Antibody
Brand: abinScience
SKU: HB604014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HB604014

Description

Anti-CD105/ENG Polyclonal Antibody (HB604014) is a rabbit polyclonal antibody detecting CD105 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CD105/ENG (Thr27-Gly581).

Target

CD105, END, Endoglin, ENG

Purification

Purified by antigen affinity column.

Accession

P17813

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Endoglin (CD105/ENG) is a ~70 kDa protein. Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis.

1. Castonguay, R. et al. (2011) The Journal of biological chemistry 286, 30034-46. PMID: 21737454

2. Nolan-Stevaux, O. et al. (2012) PloS one 7, e50920. PMID: 23300529

3. McAllister, KA. et al. (1994) Nature genetics 8, 345-51. PMID: 7894484

4. Lee, NY. et al. (2007) The Journal of biological chemistry 282, 21507-17. PMID: 17540773

5. Gougos, A. et al. (1990) The Journal of biological chemistry 265, 8361-4. PMID: 1692830

6. Alt, A. et al. (2012) PloS one 7, e29948. PMID: 22347366

7. Bellón, T. et al. (1993) European journal of immunology 23, 2340-5. PMID: 8370410

Note

For research use only.

Images

References

Datasheet