Anti-CD49d/ITGA4 Polyclonal Antibody (HY596014)

Name: Anti-CD49d/ITGA4 Polyclonal Antibody
Brand: abinScience
SKU: HY596014
Price: 168 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HY596014

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CD49d/ITGA4 (Asn35-Leu315).

Target

ITGA4, CD49d, CD49 antigen-like family member D, CD49D, VLA-4 subunit alpha, Integrin alpha-IV, Integrin alpha-4

Purification

Purified by antigen affinity column.

Accession

P13612

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Integrin alpha-4 (CD49d/ITGA4) is a ~114 kDa protein. Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1.

1. Fujita, M. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 189, 5809-19. PMID: 23125415

2. Saegusa, J. et al. (2008) The Journal of biological chemistry 283, 26107-15. PMID: 18635536

3. Fujita, M. et al. (2015) The Journal of biological chemistry 290, 259-71. PMID: 25398877

4. Morris, GE. et al. (2022) British journal of pharmacology 179, 4958-4973. PMID: 35802072

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-CD49d/ITGA4 polyclonal antibody at 1ug/mL on recombinant CD49d/ITGA4 (Catalog No. HY596012).

References

Datasheet