Anti-Clostridium tetani tetX/Tetanus toxin/TeNT Polyclonal Antibody (JN990014)

Name: Anti-Clostridium tetani tetX/Tetanus toxin/TeNT Polyclonal Antibody
Brand: abinScience
SKU: JN990014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

JN990014

Species reactivity

Clostridium tetani (strain Massachusetts / E88)

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Clostridium tetani tetX/Tetanus toxin/TeNT (Met1-Ser458).

Target

Tetanus toxin, 3.4.24.68, Tentoxylysin, Tetanus toxin light chain, Tetanus toxin chain L, Tetanus toxin heavy chain, Tetanus toxin chain H, tetX, CTC_p60, Clostridium tetani (strain Massachusetts / E88)

Purification

Purified by antigen affinity column.

Accession

P04958

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Tetanus toxin (tetX) is a ~150 kDa protein. Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-|-Phe-77' bond of synaptobrevin-2.

Note

For research use only.

Images

References

Datasheet