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Anti-Clostridium tetani tetX/Tetanus toxin Reference Antibody (SAA0800, RUO) (JN990016)

Anti-Clostridium tetani tetX/Tetanus toxin Reference Antibody (SAA0800, RUO)
Anti-Clostridium tetani tetX/Tetanus toxin Reference Antibody (SAA0800, RUO)
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Overview
Catalog No.JN990016
Description
Anti-Clostridium tetani tetX/Tetanus toxin (SAA0800) (JN990016) is a research-grade recombinant antibody targeting tetX/Tetanus toxin. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityClostridium tetani
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHuman
IsotypeIgG1
Clone IDSAA0800
Expression system Mammalian cells
Clonality Monoclonal
Target tetX/Tetanus toxin
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P04958
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesTRN0010, TT0067
Background

Tetanus toxin (tetX) is a ~150 kDa protein. Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-|-Phe-77' bond of synaptobrevin-2.

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Clostridium tetani tetX/Tetanus toxin Reference Antibody (SAA0800, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Clostridium tetani tetX/Tetanus toxin (SAA0800).

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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