Anti-Clostridium tetani tetX/Tetanus toxin Reference Antibody (Siltartoxatug, RUO) (JN990026)

Name: Anti-Clostridium tetani tetX/Tetanus toxin Reference Antibody (Siltartoxatug, RUO)
Brand: abinScience
SKU: JN990026
Price: 370 USD
Availability: InStock

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Overview

Catalog No.	JN990026
Description	Siltartoxatug (JN990026) is a research-grade recombinant antibody targeting Tetanus toxin. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Clostridium tetani (strain Massachusetts / E88)
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG1-kappa
Expression system	Mammalian cells
Clonality	Monoclonal
Target	Tetanus toxin, 3.4.24.68, Tentoxylysin, Tetanus toxin light chain, Tetanus toxin chain L, Tetanus toxin heavy chain, Tetanus toxin chain H, tetX, CTC_p60
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P04958
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	2841700-23-8
Background	Tetanus toxin (tetX) is a ~150 kDa protein. Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-\|-Phe-77' bond of synaptobrevin-2.
Note	For research use only. Not suitable for clinical or therapeutic use.