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Anti-Human AGTR2/AT2 Polyclonal Antibody (HW681014)

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Overview
Catalog No.HW681014
Description
Anti-Human AGTR2 Polyclonal Antibody (HW681014) is a rabbit polyclonal antibody detecting AGTR2. Suitable for Human.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human AGTR2 (Lys2-Asp45&Arg182-Gln206&Val321-Ser363).
Target AGTR2, AT2 receptor, Angiotensin II type-2 receptor, Type-2 angiotensin II receptor
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Purified by antigen affinity column.
Accession P50052
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Type-2 angiotensin II receptor (AGTR2) is a ~41 kDa protein. Receptor for angiotensin II, a vasoconstricting peptide. Signals primarily via a non-canonical G-protein- and beta-arrestin independent pathways. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.

1. Zhang, H. et al. (2017) Nature 544, 327-332. PMID: 28379944
2. Asada, H. et al. (2018) Nature structural & molecular biology 25, 570-576. PMID: 29967536
3. Asada, H. et al. (2020) Structure (London, England : 1993) 28, 418-425.e4. PMID: 31899086
4. Tsuzuki, S. et al. (1994) Biochemical and biophysical research communications 200, 1449-54. PMID: 8185599
5. Nouet, S. et al. (2004) The Journal of biological chemistry 279, 28989-97. PMID: 15123706
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-Human AGTR2/AT2 Polyclonal Antibody

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