

| Catalog No. | HP237025 |
|---|---|
| Description |
Anti-Human ASTL/Ovastacin Monoclonal Antibody (1A069) [1A069] (HP237025) is a mouse monoclonal antibody detecting Ovastacin in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| Species reactivity | Human |
| Applications | ELISA, IHC, WB |
| Host species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Clone ID | 1A069 |
| Immunogen | Mammalian cells - derived recombinant Human ASTL / Ovastacin (Met1-Asp431). |
| Target | Oocyte astacin, Astacin-like metalloendopeptidase, ZP2-proteinase, ASTL, Ovastacin |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | Q6HA08 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Background | Astacin-like metalloendopeptidase (ASTL/Ovastacin) is a ~45 kDa protein. Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding. |
| Note | For research use only. |

SDS-PAGE for Anti-Human ASTL/Ovastacin Monoclonal Antibody (1A069)




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