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Anti-Human ASTL/Ovastacin Polyclonal Antibody (HP237014)

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Overview
Catalog No.HP237014
Description
Anti-Human ASTL/Ovastacin Polyclonal Antibody (HP237014) is a rabbit polyclonal antibody detecting Ovastacin. Suitable for Human.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human ASTL/Ovastacin (Lys53-Ala305).
Target ASTL, Astacin-like metalloendopeptidase, EC:3.4.-.-, Oocyte astacin, Ovastacin, ZP2-proteinase
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q6HA08
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Astacin-like metalloendopeptidase (ASTL/Ovastacin) is a ~45 kDa protein. Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding.

Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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V₁ (Stock Vol.)
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Anti-Human ASTL/Ovastacin Polyclonal Antibody

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