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Anti-Human CD300a Recombinant Antibody (SAA1721) (HV400013)

Anti-Human CD300a Recombinant Antibody (SAA1721)
Anti-Human CD300a Recombinant Antibody (SAA1721)
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Overview
Catalog No.HV400013
Species reactivityHuman
ApplicationsELISA
Host speciesMouse
IsotypeIgG2a, kappa
Clone IDSAA1721
Clonality Monoclonal
Target Inhibitory receptor protein 60, IRp60, CMRF35-H, CLM-8, CMRF35-H9, CMRF35-like molecule 8, CD300A, NK inhibitory receptor, IgSF12, CD300a, CMRF35H, IRC1/IRC2, IGSF12, CD300 antigen-like family member A, CMRF-35-H9, Immunoglobulin superfamily member 12
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q9UGN4
RRID Anti-Human CD300a Antibody (SAA1721) (abinScience Cat# HV400013, RRID:AB_3727482)
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

CMRF35-like molecule 8 (CD300a) is a ~33 kDa protein. Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6.

1. Clark, GJ. et al. (2000) Tissue antigens 55, 101-9. PMID: 10746781
2. Bachelet, I. et al. (2005) Journal of immunology (Baltimore, Md. : 1950) 175, 7989-95. PMID: 16339535
3. Green, BJ. et al. (1998) International immunology 10, 891-9. PMID: 9701027
4. Kim, EJ. et al. (2012) Immunology 135, 226-35. PMID: 22043923
Note For research use only.
Images
  • Anti-Human CD300a Recombinant Antibody (SAA1721)

    SDS-PAGE

    SDS-PAGE for Anti-Human CD300a Antibody (SAA1721)

References
Formula
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