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Anti-Human CD66c/CEACAM6 Recombinant Antibody (78NCA-90), FITC (HW494217)

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Overview

Catalog No.	HW494217
Description	Anti-Human CD66c/CEACAM6 Antibody (78NCA-90), FITC [78NCA-90] (HW494217) is a mouse monoclonal antibody detecting CEACAM6 in FCM. Suitable for Human. Highlights ●Flow Cytometry — Validated for flow cytometry applications. ●Fluorescent Label — Direct conjugate for streamlined workflows.
Species reactivity	Human
Applications	FCM
Host species	Mouse
Isotype	IgG1
Clone ID	78NCA-90
Conjugation	FITC
Clonality	Monoclonal
Target	Normal cross-reacting antigen, Carcinoembryonic antigen-related cell adhesion molecule 6, CEACAM6, CD66c, NCA, Non-specific crossreacting antigen
Endotoxin level	Please contact with the lab for this information.
Accession	P40199
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Cell adhesion molecule CEACAM6 (CD66c) is a ~37 kDa protein. Cell surface glycoprotein that plays a role in cell adhesion and tumor progression. Intercellular adhesion occurs in a calcium- and fibronectin-independent manner. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM5 and CEACAM8. Heterophilic interaction with CEACAM8 occurs in activated neutrophils. Plays a role in neutrophil adhesion to cytokine-activated endothelial cells. 1. Ordoñez, C. et al. (2000) Cancer research 60, 3419-24. PMID: 10910050 2. Kuroki, M. et al. (2001) Journal of leukocyte biology 70, 543-50. PMID: 11590190 3. Kuijpers, TW. et al. (1992) The Journal of cell biology 118, 457-66. PMID: 1378450 4. Blumenthal, RD. et al. (2005) Cancer research 65, 8809-17. PMID: 16204051 5. Oikawa, S. et al. (1991) The Journal of biological chemistry 266, 7995-8001. PMID: 2022629 6. Oikawa, S. et al. (1989) Biochemical and biophysical research communications 164, 39-45. PMID: 2803308 7. Yamanaka, T. et al. (1996) Protein expression and purification 7, 438-46. PMID: 8776764
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Human CD66c/CEACAM6 Recombinant Antibody (78NCA-90), FITC.pdf

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Anti-Human CD66c/CEACAM6 Recombinant Antibody (78NCA-90), FITC