

| Catalog No. | HB198013 | ||||
|---|---|---|---|---|---|
| Description |
Anti-Human CD72 Nanobody (NbD4) [NbD4] (HB198013) is a alpaca monoclonal antibody detecting CD72 in ELISA. Suitable for Human.
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| Species reactivity | Human | ||||
| Applications | ELISA | ||||
| Host species | Alpaca | ||||
| Isotype | VHH-8His-Cys-tag | ||||
| Clone ID | NbD4 | ||||
| Clonality | Monoclonal | ||||
| Target | CD72, Lyb-2, B-cell differentiation antigen CD72 | ||||
| Endotoxin level | Please contact with the lab for this information. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | P21854 | ||||
| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Background | B-cell differentiation antigen CD72 is a ~40 kDa protein. Co-receptor of B cell receptor (BCR) that plays both positive and negative roles on B-cell functions. Recognizes the Sm/ribonucleoprotein (RNP) self-antigen ligand, and coligation of CD72 and BCR inhibits BCR signaling. Mechanistically, ligand binding leads to the recruitment of PTPN6/SHP-1 to the BCR complex which is inhibitory to BCR signaling. Also acts as a ligand for CD5 and thereby plays a critical role in maintaining regulatory T and B-cell homeostasis. | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human CD72 Nanobody (NbD4)




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