Anti-Human CD8 alpha Monoclonal Antibody (1A482) (HF815015)

Name: Anti-Human CD8 alpha Monoclonal Antibody (1A482)
Brand: abinScience
SKU: HF815015
Price: 106 USD
Availability: InStock

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Overview

Catalog No.	HF815015
Description	Anti-Human CD8A Monoclonal Antibody (1A482) [1A482] (HF815015) is a mouse monoclonal antibody detecting CD8a in ELISA, IHC, WB. Suitable for Human. Highlights ●Recombinant — Superior batch-to-batch reproducibility with defined sequences. ●Multi-Application — Validated across multiple applications.
Species reactivity	Human
Applications	ELISA, IHC, WB
Host species	Mouse
Isotype	IgG
Clone ID	1A482
Clonality	Monoclonal
Immunogen	E. coli - derived recombinant human CD8A (Ser22-Asp182).
Target	T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2, CD8a, CD8A
Purification	Protein A/G purified from cell culture supernatant.
Accession	P01732
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	T-cell surface glycoprotein CD8 alpha chain (CD8A) is a ~25 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.
Note	For research use only.