Anti-Human Fibronectin/EDB Recombinant Antibody (SAA1375) (HY259023)

Name: Anti-Human Fibronectin/EDB Recombinant Antibody (SAA1375)
Brand: abinScience
SKU: HY259023
Price: 126 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HY259023

Species reactivity

Human

Applications

Blocking, ELISA, IHC, WB

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1375

Clonality

Monoclonal

Target

Cold-insoluble globulin, CIG, FN, Fibronectin, FN1, EDB, EDB-FN

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P02751

RRID

Anti-Human EDB/EDB-FN Antibody (SAA1375) (abinScience Cat# HY259023, RRID:AB_3726892)
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Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Fibronectin (EDB) is a ~272 kDa protein. Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts. Acts as a ligand for the LILRB4 receptor, inhibiting FCGR1A/CD64-mediated monocyte activation.