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Anti-Human Guanylyl Cyclase C/GUCY2C Recombinant Antibody (SAA2394) (HB626013)

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Anti-Human Guanylyl Cyclase C/GUCY2C Recombinant Antibody (SAA2394)
Anti-Human Guanylyl Cyclase C/GUCY2C Recombinant Antibody (SAA2394)
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Overview
Catalog No.HB626013
Description
Anti-Human Guanylyl Cyclase C/GUCY2C Recombinant Antibody (SAA2394) (HB626013) is a mouse monoclonal antibody detecting Guanylyl Cyclase C/GUCY2C in ELISA. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
Species reactivityHuman
ApplicationsELISA
Host speciesMouse
ClonalityMonoclonal
IsotypeIgG2a, kappa
Clone IDSAA2394
Target Guanylyl cyclase C, GC-C, EC:4.6.1.2, Heat-stable enterotoxin receptor, STA receptor, hSTAR, Intestinal guanylate cyclase, GUCY2C, GUC2C, STAR
Endotoxin level < 10 EU/mg as determined by LAL method.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P25092
Form Liquid
Storage buffer 0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Background

Guanylyl cyclase C (GUCY2C) is a ~123 kDa protein. Guanylyl cyclase that catalyzes synthesis of cyclic GMP (cGMP) from GTP. Receptor for the E.coli heat-stable enterotoxin; E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GUCY2C. Also activated by the endogenous peptides guanylin and uroguanylin.

1. Scott, RO. et al. (2002) The Journal of biological chemistry 277, 22934-41. PMID: 11950846
2. Singh, S. et al. (1991) Biochemical and biophysical research communications 179, 1455-63. PMID: 1718270
3. Fiskerstrand, T. et al. (2012) The New England journal of medicine 366, 1586-95. PMID: 22436048
4. Romi, H. et al. (2012) American journal of human genetics 90, 893-9. PMID: 22521417
5. Arshad, N. et al. (2013) The Journal of biological chemistry 288, 3907-17. PMID: 23269669
6. de Sauvage, FJ. et al. (1991) The Journal of biological chemistry 266, 17912-8. PMID: 1680854
7. Mann, EA. et al. (1993) The American journal of physiology 264, G172-8. PMID: 8381596
Note For research use only.
Isotype Control Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)
Images
  • Anti-Human Guanylyl Cyclase C/GUCY2C Recombinant Antibody (SAA2394)

    SDS-PAGE

    SDS-PAGE for Anti-Human GUCY2C Antibody (SAA2394)

References
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human Guanylyl Cyclase C/GUCY2C Recombinant Antibody (SAA2394)

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