Anti-Human GUCY2C Recombinant Antibody (SAA2394) (HB626013)

Name: Anti-Human GUCY2C Recombinant Antibody (SAA2394)
Brand: abinScience
SKU: HB626013
Price: 126 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HB626013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA2394

Clonality

Monoclonal

Target

Guanylyl cyclase C, GC-C, EC:4.6.1.2, Heat-stable enterotoxin receptor, STA receptor, hSTAR, Intestinal guanylate cyclase, GUCY2C, GUC2C, STAR

Endotoxin level

<10 EU/mg

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P25092

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Background

Guanylyl cyclase C (GUCY2C) is a ~123 kDa protein. Guanylyl cyclase that catalyzes synthesis of cyclic GMP (cGMP) from GTP. Receptor for the E.coli heat-stable enterotoxin; E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GUCY2C. Also activated by the endogenous peptides guanylin and uroguanylin.

1. Scott, RO. et al. (2002) The Journal of biological chemistry 277, 22934-41. PMID: 11950846

2. Singh, S. et al. (1991) Biochemical and biophysical research communications 179, 1455-63. PMID: 1718270

3. Fiskerstrand, T. et al. (2012) The New England journal of medicine 366, 1586-95. PMID: 22436048

4. Romi, H. et al. (2012) American journal of human genetics 90, 893-9. PMID: 22521417

5. Arshad, N. et al. (2013) The Journal of biological chemistry 288, 3907-17. PMID: 23269669

6. de Sauvage, FJ. et al. (1991) The Journal of biological chemistry 266, 17912-8. PMID: 1680854

7. Mann, EA. et al. (1993) The American journal of physiology 264, G172-8. PMID: 8381596

Note

For research use only

Isotype Control

Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)

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