Anti-Human Guanylyl Cyclase C/GUCY2C Recombinant Nanobody (SAA2687) (HB626023)

Name: Anti-Human Guanylyl Cyclase C/GUCY2C Recombinant Nanobody (SAA2687)
Brand: abinScience
SKU: HB626023
Price: 191 USD
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Overview

Catalog No.	HB626023
Description	Anti-Human GUCY2C Nanobody (SAA2687) [SAA2687] (HB626023) is a alpaca monoclonal antibody detecting GUCY2C in ELISA. Suitable for Human.
Species reactivity	Human
Applications	ELISA
Host species	Alpaca
Clonality	Monoclonal
Isotype	VHH-8His
Clone ID	SAA2687
Target	EC:4.6.1.2, GC-C, GUC2C, GUCY2C, Guanylyl cyclase C, Heat-stable enterotoxin receptor, Intestinal guanylate cyclase, STA receptor, STAR, hSTAR
Endotoxin level	< 10 EU/mg as determined by LAL method.
Purity	>95% as determined by SDS-PAGE.
Purification	Purified by Nickel column.
Accession	P25092
Form	Liquid
Storage buffer	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Guanylyl cyclase C (GUCY2C) is a ~123 kDa protein. Guanylyl cyclase that catalyzes synthesis of cyclic GMP (cGMP) from GTP. Receptor for the E.coli heat-stable enterotoxin; E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GUCY2C. Also activated by the endogenous peptides guanylin and uroguanylin. 1. Scott, RO. et al. (2002) The Journal of biological chemistry 277, 22934-41. PMID: 11950846 2. Singh, S. et al. (1991) Biochemical and biophysical research communications 179, 1455-63. PMID: 1718270 3. Fiskerstrand, T. et al. (2012) The New England journal of medicine 366, 1586-95. PMID: 22436048 4. Romi, H. et al. (2012) American journal of human genetics 90, 893-9. PMID: 22521417 5. Arshad, N. et al. (2013) The Journal of biological chemistry 288, 3907-17. PMID: 23269669 6. de Sauvage, FJ. et al. (1991) The Journal of biological chemistry 266, 17912-8. PMID: 1680854 7. Mann, EA. et al. (1993) The American journal of physiology 264, G172-8. PMID: 8381596
Note	For research use only.

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Anti-Human Guanylyl Cyclase C/GUCY2C Recombinant Nanobody (SAA2687).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Anti-Human Guanylyl Cyclase C/GUCY2C Recombinant Nanobody (SAA2687) (HB626023)

Overview

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References

Datasheet

SDS