Anti-Human HCRTR1/OX1R Recombinant Antibody (SAA1954) (HT363013)

Name: Anti-Human HCRTR1/OX1R Recombinant Antibody (SAA1954)
Brand: abinScience
SKU: HT363013
Price: 196 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HT363013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1954

Clonality

Monoclonal

Target

Hypocretin receptor type 1, Ox1-R, Ox1R, Ox-1-R, Orexin receptor type 1, HCRTR1

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O43613

RRID

Anti-Human HCRTR1/OX1R Antibody (SAA1954) (abinScience Cat# HT363013, RRID:AB_3727718)
_x005F_x000D_

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Orexin/Hypocretin receptor type 1 (HCRTR1/OX1R) is a ~47 kDa protein. G-protein coupled receptor that binds the neuropeptide orexin-A with high affinity, and orexin-B with lower affinity, two peptides derived from a common precursor, prepro-orexin. Its activity is mediated via a G(q)-protein-coupled pathway, which activates the phosphatidylinositol-calcium second messenger system in response to orexin-A binding. In addition to G(q)-mediated signaling, orexin-A stimulation also promotes beta-arrestin recruitment, leading to receptor internalization. Plays a significant role in the regulation of food intake.

1. Hellmann, J. et al. (2020) Proceedings of the National Academy of Sciences of the United States of America 117, 18059-18067. PMID: 32669442

2. Sakurai, T. et al. (1998) Cell 92, 573-85. PMID: 9491897

3. Milasta, S. et al. (2005) The Biochemical journal 387, 573-84. PMID: 15683363

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human HCRTR1/OX1R Antibody (SAA1954)

References

Datasheet

Anti-Human HCRTR1/OX1R Recombinant Antibody (SAA1954).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human HCRTR1/OX1R Recombinant Antibody (SAA1954) (HT363013)

Overview

Images

References

Datasheet

SDS

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