

| Catalog No. | HV556013 | ||||
|---|---|---|---|---|---|
| Species reactivity | Human | ||||
| Applications | ELISA, IHC, FCM | ||||
| Host species | Human | ||||
| Isotype | IgG | ||||
| Clone ID | SAA2359 | ||||
| Clonality | Monoclonal | ||||
| Target | Interleukin-1 receptor accessory protein, IL-1 receptor accessory protein, IL-1RAcP, EC:3.2.2.6, Interleukin-1 receptor 3, IL-1R-3, IL-1R3, IL1RAP, C3orf13, IL1R3 | ||||
| Endotoxin level | Please contact with the lab for this information. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | Q9NPH3 | ||||
| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
| ||||
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Background | Interleukin-1 receptor accessory protein (IL1RAP) is a ~65 kDa protein. Coreceptor for IL1RL2 in the IL-36 signaling system. Coreceptor with IL1R1 in the IL-1 signaling system. Associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Recruits TOLLIP to the signaling complex. | ||||
| Note | For research use only |

SDS-PAGE for Anti-Human IL1RAP Antibody (SAA2359)




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