Anti-Human LRRC32/GARP Recombinant Antibody (SAA0543), FITC (HC573117)

Name: Anti-Human LRRC32/GARP Recombinant Antibody (SAA0543), FITC
Brand: abinScience
SKU: HC573117
Price: 196 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD):

Spec:

50T
100T

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.	HC573117
Species reactivity	Human
Applications	ELISA, FCM
Host species	Mouse
Isotype	IgG2a, kappa
Clone ID	SAA0543
Conjugation	FITC
Clonality	Monoclonal
Target	GARP, Leucine-rich repeat-containing protein 32, Glycoprotein A repetitions predominant, D11S833E, Garpin, Transforming growth factor beta activator LRRC32, LRRC32
Endotoxin level	Please contact with the lab for this information.
Associated products	Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), FITC
Accession	Q14392
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Transforming growth factor beta activator LRRC32 (GARP) is a ~71 kDa protein. Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta. Able to outcompete LTBP1 for binding to LAP regulatory chain of TGF-beta. Controls activation of TGF-beta-1 (TGFB1) on the surface of activated regulatory T-cells (Tregs). Required for epithelial fusion during palate development by regulating activation of TGF-beta-3 (TGFB3). 1. Tran, DQ. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 13445-50. PMID: 19651619 2. Stockis, J. et al. (2009) European journal of immunology 39, 3315-22. PMID: 19750484 3. Wang, R. et al. (2012) Molecular biology of the cell 23, 1129-39. PMID: 22278742
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

Images

References

Datasheet

Anti-Human LRRC32/GARP Recombinant Antibody (SAA0543), FITC.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human LRRC32/GARP Recombinant Antibody (SAA0543), FITC (HC573117)

Overview

Images

References

Datasheet

SDS

Quick access

Contact Us