Anti-Human VIPR1/VPAC1 Recombinant Antibody (SAA1972) (HB111013)

Name: Anti-Human VIPR1/VPAC1 Recombinant Antibody (SAA1972)
Brand: abinScience
SKU: HB111013
Price: 196 USD
Availability: InStock

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1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HB111013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1972

Clonality

Monoclonal

Target

VIP-R-1, PACAP-R2, VIPR1, PACAP-R-2, Pituitary adenylate cyclase-activating polypeptide type II receptor, PACAP type II receptor, VPAC1, Vasoactive intestinal polypeptide receptor 1

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P32241

RRID

Anti-Human VIPR1/VPAC1 Antibody (SAA1972) (abinScience Cat# HB111013, RRID:AB_3727736)
_x005F_x005F_x000D_

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Vasoactive intestinal polypeptide receptor 1 (VIPR1/VPAC1) is a ~51 kDa protein. G protein-coupled receptor activated by the neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (ADCYAP1/PACAP). Binds VIP and both PACAP27 and PACAP38 bioactive peptides with the following order of ligand affinity VIP = PACAP27 > PACAP38. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. Activates cAMP-dependent pathway.

1. Xu, Y. et al. (2022) Nature communications 13, 2272. PMID: 35477937

2. Piper, SJ. et al. (2022) Nature communications 13, 7013. PMID: 36385145

3. Couvineau, A. et al. (1994) Biochemical and biophysical research communications 200, 769-76. PMID: 8179610

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human VIPR1/VPAC1 Antibody (SAA1972)

References

Datasheet

Anti-Human VIPR1/VPAC1 Recombinant Antibody (SAA1972).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human VIPR1/VPAC1 Recombinant Antibody (SAA1972) (HB111013)

Overview

Images

References

Datasheet

SDS

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