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Anti-Omalizumab ELISA Kit (AV064018)

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Overview
Catalog No.AV064018
Description
Anti-Omalizumab ELISA Kit (AV064018) — Quantitative sandwich ELISA for Anti-Omalizumab. Sample: Plasma, Serum. Range: 156.25 - 10, 000 ng/mL.
Highlights
  • Sandwich Format — High specificity, reliable quantification.
  • Ready-to-Use — Complete kit with pre-coated plates included.
Sample typePlasma, Serum
Sensitivity0.25 ng/mL
Range156.25 - 10, 000 ng/mL
Accession CAS: 242138-07-4
Applications ELISA
Detection method Colorimetric
Assay type Quantitative
Recovery 80-120%
Shipping 2-8 ℃
Stability and Storage The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
Specifications

Omalizumab

Alternate NamesIGE25, olizumab, pSVIE26, rhuMab-E25, 242138-07-4
Background

Immunoglobulin heavy constant epsilon (Omalizumab) is a ~59 kDa protein. Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.

1. Schroeder, HW. et al. (2010) The Journal of allergy and clinical immunology 125, S41-52. PMID: 20176268
2. McHeyzer-Williams, M. et al. (2011) Nature reviews. Immunology 12, 24-34. PMID: 22158414
3. Teng, G. et al. (2007) Annual review of genetics 41, 107-20. PMID: 17576170
Note For Research Use Only.
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References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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