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Anti-Omalizumab Neutralizing Antibody ELISA kit (AV064518)

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Overview
Catalog No.AV064518
Description
Anti-Omalizumab Neutralizing Antibody ELISA kit (AV064518) — Quantitative sandwich ELISA for Anti-Omalizumab Neutralizing Antibody. Sample: Plasma, Serum. Range: 156.25 - 10, 000 ng/mL. Sensitivity: 82.6 ng/mL.
Highlights
  • Sandwich Format — High specificity, reliable quantification.
  • High Sensitivity — Optimized for low-abundance target detection.
  • Ready-to-Use — Complete kit with pre-coated plates included.
Sample typePlasma, Serum
Sensitivity82.6 ng/mL
Range156.25 - 10, 000 ng/mL
Accession CAS: 242138-07-4
Applications ELISA
Detection method Colorimetric
Assay type Quantitative
Recovery 80-120%
Shipping 2-8 ℃
Stability and Storage When the kit was stored at the recommended temperature for 6 months, the signal intensity decreased by less than 20%. For unopened kits, if you want to prolong the storage time, please store the Standard, Detection A, Detection B and Microplate at - 20℃, the rest reagents should be store at 4℃.
Specifications

Omalizumab

Alternate NamesIGE25, olizumab, pSVIE26, rhuMab-E25, 242138-07-4
Background

Immunoglobulin heavy constant epsilon (Omalizumab) is a ~59 kDa protein. Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.

1. Schroeder, HW. et al. (2010) The Journal of allergy and clinical immunology 125, S41-52. PMID: 20176268
2. McHeyzer-Williams, M. et al. (2011) Nature reviews. Immunology 12, 24-34. PMID: 22158414
3. Teng, G. et al. (2007) Annual review of genetics 41, 107-20. PMID: 17576170
Note For Research Use Only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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