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Anti-Porcine CD163 Polyclonal Antibody (SV831014)

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Overview
Catalog No.SV831014
Description
Anti-Pig CD163 Polyclonal Antibody (SV831014) is a rabbit polyclonal antibody detecting CD163. Suitable for Human.
Species reactivityPorcine
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Pig CD163 (Arg475-Ser577).
Target CD163, M130, Scavenger receptor cysteine-rich type 1 protein M130, Soluble CD163, sCD163
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q2VL90
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Scavenger receptor cysteine-rich type 1 protein M130 (CD163) is a ~120 kDa protein. Involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. May play a role in the process of infection of porcine monocytes/macrophages by African swine fever virus (ASFV).

Note For research use only
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Anti-Porcine CD163 Polyclonal Antibody

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