







| Catalog No. | HC336020 | ||||
|---|---|---|---|---|---|
| Description |
InVivoMAb Anti-Human CD137/TNFRSF9/4-1BB Antibody (Iv0138) [Iv0138] (HC336020) is a human monoclonal antibody detecting Tumor necrosis factor receptor superfamily member 9 in ELISA, Neutralization. Suitable for Human.
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| Species reactivity | Human | ||||
| Applications | ELISA, FCM, Neutralization | ||||
| Host species | Human | ||||
| Clonality | Monoclonal | ||||
| Isotype | IgG1, kappa | ||||
| Clone ID | Iv0138 | ||||
| Tested applications | FCM | ||||
| Target | 4-1BB ligand receptor, CD137, CDw137, ILA, T-cell antigen 4-1BB homolog, T-cell antigen ILA, TNFRSF9, Tumor necrosis factor receptor superfamily member 9 | ||||
| Endotoxin level | < 1 EU/mg | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Associated products | pH 7.4 Dilution Buffer | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | Q07011 | ||||
| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Background | Tumor necrosis factor receptor superfamily member 9 (CD137/4-1BB) is a ~27 kDa protein. Receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (Probable). | ||||
| Note | For research use only. Not suitable for clinical or therapeutic use. | ||||
| Isotype Control | Anti-LASV GPC Recombinant Antibody (Fab 37.7) (VK453013) |

Detects CD137/TNFRSF9/4-1BB in indirect ELISAs.

SDS-PAGE for InVivoMAb Anti-Human CD137/TNFRSF9/4-1BB Antibody (Iv0138).

Flow-cytometry using PE anti-human CD137 antibody. HDLM-2 cells were stained with an irrelevant antibody (Blue Histogram) or an PE anti-human CD137 monoclonal antibody (Catalog: HC336020, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

Immunofluorescence staining of HDLM2 with Human monoclonal antibody (20ug/ml, overnight at 4°C), followed by Alexa Fluor-488-conjugated secondary antibody (6.5ug/ml, 50minutes at room temperature). The target protein was detected in the cell membrane.




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