

| Catalog No. | HV678010 |
|---|---|
| Description |
InVivoMAb Anti-Human IL31 Antibody (Iv0206) [Iv0206] (HV678010) is a human monoclonal antibody detecting IL-31 in ELISA, Neutralization. Suitable for Human.
|
| Species reactivity | Human |
| Applications | ELISA, Neutralization |
| Host species | Human |
| Isotype | IgG1 |
| Clone ID | Iv0206 |
| Clonality | Monoclonal |
| Target | IL-31, Interleukin-31, IL31 |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | Q6EBC2 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Background | Interleukin-31 (IL31) is a ~18 kDa protein. Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. May function in skin immunity. Enhances myeloid progenitor cell survival in vitro. Induces RETNLA and serum amyloid A protein expression in macrophages. 1. Dillon, SR. et al. (2004) Nature immunology 5, 752-60. PMID: 15184896 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for InVivoMAb Anti-Human IL31 Antibody (Iv0206)




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