Anti-Human IL-31 Reference Antibody (mAb33, RUO) (HV678026)

Name: Anti-Human IL-31 Reference Antibody (mAb33, RUO)
Brand: abinScience
SKU: HV678026
Price: 370 USD
Availability: InStock

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Overview

Catalog No.	HV678026
Description	Anti-Human IL31 Antibody (mAb33) (HV678026) is a research-grade recombinant antibody targeting IL-31. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG1
Clone ID	mAb33
Expression system	Mammalian cells
Clonality	Monoclonal
Target	IL-31, Interleukin-31, IL31
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q6EBC2
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Interleukin-31 (IL31) is a ~18 kDa protein. Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. May function in skin immunity. Enhances myeloid progenitor cell survival in vitro. Induces RETNLA and serum amyloid A protein expression in macrophages. 1. Dillon, SR. et al. (2004) Nature immunology 5, 752-60. PMID: 15184896
Note	For research use only. Not suitable for clinical or therapeutic use.