Human AGTR2 Recombinant Protein (N-His-KSI) (HW681012)

Name: Human AGTR2 Recombinant Protein (N-His-KSI)
Brand: abinScience
SKU: HW681012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HW681012
Description	Recombinant Human AGTR2 Protein, N-His-KSI (HW681012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	P50052
Protein length	Lys2-Asp45&Arg182-Gln206&Val321-Ser363
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	AGTR2, AT2 receptor, Angiotensin II type-2 receptor, Type-2 angiotensin II receptor
Background	Type-2 angiotensin II receptor is a ~41 kDa protein. Receptor for angiotensin II, a vasoconstricting peptide. Signals primarily via a non-canonical G-protein- and beta-arrestin independent pathways. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation. 1. Zhang, H. et al. (2017) Nature 544, 327-332. PMID: 28379944 2. Asada, H. et al. (2018) Nature structural & molecular biology 25, 570-576. PMID: 29967536 3. Asada, H. et al. (2020) Structure (London, England : 1993) 28, 418-425.e4. PMID: 31899086 4. Tsuzuki, S. et al. (1994) Biochemical and biophysical research communications 200, 1449-54. PMID: 8185599 5. Nouet, S. et al. (2004) The Journal of biological chemistry 279, 28989-97. PMID: 15123706
Note	For research use only

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Datasheet

Human AGTR2 Recombinant Protein (N-His-KSI).pdf

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Formula

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Human AGTR2 Recombinant Protein (N-His-KSI) (HW681012)

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