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Human IL-17RA/IL-17R Recombinant Protein (N-His) (HV263022)

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Overview
Catalog No.HV263022
Description
Recombinant Human IL17RA Protein, N-His (HV263022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
  • E. coli Expression — High-yield, cost-effective production.
  • High Purity — >90% as determined by SDS-PAGE.
Expression systemE. coli
AccessionQ96F46
Protein lengthAsn49-Ser302
ApplicationsELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
SpeciesHomo sapiens (Human)
Nature Recombinant
Endotoxin level Please contact with the lab for this information.
Purity >90% as determined by SDS-PAGE.
Form Lyophilized
Storage buffer Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitution Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesCD217, CDw217, IL-17 receptor A, IL-17RA, IL17R, IL17RA, Interleukin-17 receptor A
Background

Interleukin-17 receptor A is a ~96 kDa protein. Receptor for IL17A and IL17F, major effector cytokines of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity. Receptor for IL17A. Receptor for IL17F. Binds to IL17A with higher affinity than to IL17F. Binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC.

1. Kuestner, RE. et al. (2007) Journal of immunology (Baltimore, Md. : 1950) 179, 5462-73. PMID: 17911633
2. Yao, Z. et al. (1997) Cytokine 9, 794-800. PMID: 9367539
3. Ely, LK. et al. (2009) Nature immunology 10, 1245-51. PMID: 19838198
4. Toy, D. et al. (2006) Journal of immunology (Baltimore, Md. : 1950) 177, 36-9. PMID: 16785495
5. Wright, JF. et al. (2008) Journal of immunology (Baltimore, Md. : 1950) 181, 2799-805. PMID: 18684971
6. Puel, A. et al. (2011) Science (New York, N.Y.) 332, 65-8. PMID: 21350122
7. Boisson, B. et al. (2013) Immunity 39, 676-86. PMID: 24120361
Note For research use only
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Formula
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