Human LRRC15/LIB Recombinant Protein (C-Fc) (HV777021)

Name: Human LRRC15/LIB Recombinant Protein (C-Fc)
Brand: abinScience
SKU: HV777021
Price: 298 USD
Availability: InStock

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Overview

Catalog No.	HV777021
Description	Recombinant Human LRRC15/LIB Protein, C-Fc (HV777021) expressed in Mammalian Cells, spanning Tyr22-Gly538. Purity: >90% by SDS-PAGE. Highlights ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	Mammalian cells
Accession	Q8TF66
Protein length	Tyr22-Gly538
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	86.11 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	LIB, LRRC15, Leucine-rich repeat protein induced by beta-amyloid homolog, Leucine-rich repeat-containing protein 15, hLib
Background	Leucine-rich repeat-containing protein 15 is a ~64 kDa protein. (Microbial infection) Modulates the ability of SARS-CoV-2 to infect host cells through interaction with the spike protein. Does not act as a SARS-CoV-2 entry receptor but sequesters virions and antagonizes in trans SARS-CoV-2 infection of ACE2(+) cells when expressed on nearby cells. 1. Song, J. et al. (2022) PLoS biology 20, e3001805. PMID: 36228039 2. Shilts, J. et al. (2023) PLoS biology 21, e3001959. PMID: 36735681 3. Loo, L. et al. (2023) PLoS biology 21, e3001967. PMID: 36757924
Note	For research use only

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Datasheet

Human LRRC15/LIB Recombinant Protein (C-Fc).pdf

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Human LRRC15/LIB Recombinant Protein (C-Fc) (HV777021)

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