Anti-Human ANXA1/Annexin A1 Reference Antibody (Amesotatug, RUO) (HY216016)

Name: Anti-Human ANXA1/Annexin A1 Reference Antibody (Amesotatug, RUO)
Brand: abinScience
SKU: HY216016
Price: 370 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HY216016

Description

Research Grade amesotatug (HY216016) is a human monoclonal antibody. Suitable for Human.

Species reactivity

Human

Applications

ELISA, Bioactivity: FACS, Functional assay, Research in vivo

Host species

Human

Clonality

Monoclonal

Isotype

IgG1, kappa

Target

ANX1, ANXA1, Annexin A1, Annexin Ac2-26, Annexin I, Annexin-1, Calpactin II, Calpactin-2, Chromobindin-9, LPC1, Lipocortin I, Phospholipase A2 inhibitory protein, p35

Endotoxin level

< 10 EU/mg

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P04083

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Annexin A1 (ANXA1) is a ~38 kDa protein. Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Contributes to the adaptive immune response by enhancing signaling cascades that are triggered by T-cell activation, regulates differentiation and proliferation of activated T cells. Promotes the differentiation of T cells into Th1 cells and negatively regulates differentiation into Th2 cells.

1. Arcone, R. et al. (1993) European journal of biochemistry 211, 347-55. PMID: 8425544

2. D'Acquisto, F. et al. (2007) Blood 109, 1095-102. PMID: 17008549

3. McArthur, S. et al. (2009) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 23, 4000-10. PMID: 19625660

4. Pepinsky, RB. et al. (1989) The Biochemical journal 263, 97-103. PMID: 2532504

5. Mailliard, WS. et al. (1996) The Journal of biological chemistry 271, 719-25. PMID: 8557678

Note

For research use only.

Images

References

Datasheet